Advice

Following a full submission.

Topiramate is accepted for restricted use within NHS Scotland for its extended (monotherapy) indication. It should be initiated only by physicians who have appropriate experience in the treatment of epilepsy.

Topiramate should be used principally in patients who have not benefited from treatment with an older anti-convulsant drug such as carbamazepine or sodium valproate, or for whom these drugs are unsuitable because of contraindications, interactions or poor tolerance. Its use for second-line therapy in epilepsy is unaffected by this recommendation.

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Medicine details

Medicine name:
Topiramate (Topamax)
SMC ID:
75/03
Indication:
Epilepsy
Pharmaceutical company
Janssen-Cilag Ltd
BNF chapter
Central nervous system
Submission type
Full
Status
Restricted
Date advice published:
12 January 2004