Advice

in the absence of a submission from the holder of the marketing authorisation:

ibrutinib (Imbruvica®) is not recommended for use within NHSScotland.

Indication under review: As a single agent for the treatment of adult patients with Waldenström’s macroglobulinaemia who have received at least one prior therapy, or in first line treatment for patients unsuitable for chemo-immunotherapy.

The holder of the marketing authorisation has not made a submission to SMC regarding this product in this setting. As a result we cannot recommend its use within NHSScotland.

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Medicine details

Medicine name:
ibrutinib (Imbruvica)
SMC ID:
SMC2245
Indication:

As a single agent for the treatment of adult patients with Waldenström’s macroglobulinaemia who have received at least one prior therapy, or in first line treatment for patients unsuitable for chemo-immunotherapy.

Pharmaceutical company
Janssen-Cilag Ltd
BNF chapter
Submission type
Non submission
Status
Not recommended
Date advice published:
11 November 2019