Advice
Appropriate for use in NHS Scotland.
RECOMMENDATION
Compared with enoxaparin, fondaparinux has been shown to be associated with fewer thrombo-embolic events and a generally similar incidence of major bleeding. It is licensed for post-operative initiation, and this represents an advantage where regional anaesthesia and/or catheterisation are planned. It is predicted to be a cost effective alternative to enoxaparin in a robust economic model.
It may be considered for patients for whom antithrombotic therapy is appropriate, recognising that other antithrombotic agents and other approaches to prophylaxis may be more suitable in some situations.
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Medicine details
- Medicine name:
- fondaparinux (Arixtra)
- SMC ID:
- 18/02
- Indication:
- Antithrombotic therapy
- Pharmaceutical company
- Sanofi-Aventis
- BNF chapter
- Cardiovascular system
- Submission type
- Full
- Status
- Accepted
- Date advice published
- 08 November 2002