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Esomeprazole (Nexium®)

Advice

Following a full submission

Esomeprazole (Nexium®) is not recommended for use within NHS Scotland for the healing of gastric ulcers associated with non-steroidal anti-inflammatory drug (NSAID) therapy.

In the treatment of gastric ulcers associated with NSAID therapy, esomeprazole produced greater healing rates than a histamine-H2 antagonist. However, there are no comparisons of esomeprazole with other proton pump inhibitors for this indication. The economic case has not been demonstrated.

Drug Details

Drug Name: Esomeprazole (Nexium®)
SMC Drug ID: 274/06
Manufacturer: AstraZeneca UK Ltd
Indication: Healing of gastric ulcers associated with non-steroidal anti-inflammatory drug (NSAID) therapy,
BNF Category:
Submission Type: Full submission
Status: Not Recommended
Date Advice Published: 12 June 2006

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