You are here:

Archived: botulinum toxin type a (Botox)

Advice

Following a resubmission:

botulinum toxin type A (Botox®) is not recommended for use within NHS Scotland.

Indication under review: the prophylaxis of headaches in adults with chronic migraine (headaches on at least 15 days per month of which at least 8 days are with migraine).

In pooled analysis of the two pivotal phase III studies, botulinum toxin type A significantly reduced the frequency of headache days compared with placebo.

The submitting company did not present a sufficiently robust clinical and economic analysis to gain acceptance by SMC.

Drug Details

Drug Name: botulinum toxin type a (Botox)
SMC Drug ID: 692/11
Manufacturer: Allergan Ltd
Indication: Prophylaxis of headaches in adults with chronic migraine (CM) (headaches on at least 15 days per month of which at least eight days are with migraine).
BNF Category:
Sub Category: 4.9 Drugs used in Parkinsonism and related disorders
Submission Type: Resubmission
Status: Not Recommended
Date Advice Published: 8 April 2013

Current Advice

Resubmission 13 February 2017

Archived Advice

Full submission 10 April 2011

Back