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Palonosetron 250 micrograms solution for injection (Aloxi®)

Advice

Following a full submission.

Palonosetron (Aloxi) is accepted for use within NHS Scotland for the prevention of acute nausea and vomiting associated with highly emetogenic cancer chemotherapy and the prevention of nausea and vomiting associated with moderately emetogenic cancer chemotherapy.

It is as effective as other 5HT3 antagonists in preventing emesis when given as a single intravenous injection following highly emetogenic chemotherapy (HEC) in the acute phase and moderately emetogenic chemotherapy (MEC) in the acute and delayed phases post–chemotherapy.

Drug Details

Drug Name: Palonosetron 250 micrograms solution for injection (Aloxi®)
SMC Drug ID: 208/05
Manufacturer: Cambridge Laboratories
Indication: Prevention of acute nausea and vomiting associated with highly-emetogenic cancer chemotherapy and the prevention of nausea and vomiting associated with moderately -emetogenic cancer chemotherapy
BNF Category:
Sub Category: 4.6 Drugs used in nausea and vertigo
Submission Type: Full submission
Status: Accepted
Date Advice Published: 7 November 2005

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