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Olanzapine (Zyprexa)


Following a full submission.

Olanzapine (Zyprexa?) is accepted for use within NHS Scotland for the prevention of recurrence in patients with bipolar disorder whose manic episode has responded to olanzapine treatment.

Olanzapine has been shown to be significantly superior to placebo in delaying symptomatic relapse of mania or depression and of mania alone. Apart from weight gain, somnolence and treatment-emergent depression, most significant differences between olanzapine and active competitors favoured olanzapine.

Drug Details

Drug Name: Olanzapine (Zyprexa)
SMC Drug ID: 98/04
Manufacturer: Eli Lilly and Company Ltd
Indication: for prevention of recurrence in bipolar disorder
BNF Category:
Sub Category: 4.2 Drugs used in psychoses and related disorders
Submission Type: Full submission
Status: Accepted
Date Advice Published: 10 May 2004