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Bemiparin, 2500 IU in 0.2 ml injection for sub-cutaneous administration (Zibor®)

Advice

Following a full submission

Bemiparin (Zibor) is not recommended for use within NHS Scotland for the prevention of thromboembolic disease in patients undergoing general surgery.

In one small study neither bemiparin nor unfractionated heparin was associated with thromboembolic complications following abdominal surgery but major bleeding and wound haematoma were more common with unfractionated heparin. Bemiparin has not been evaluated in other general surgery settings or against other low molecular weight heparins.

No evidence of the cost effectiveness of bemiparin during general surgery has been presented by the manufacturer.

Drug Details

Drug Name: Bemiparin, 2500 IU in 0.2 ml injection for sub-cutaneous administration (Zibor®)
SMC Drug ID: 203/05
Manufacturer: Amdipharm PLC
Indication: Prevention of thromboembolic disease in patients undergoing general surgery
BNF Category:
Sub Category: 2.8 Anticoagulants and protamine
Submission Type: Full submission
Status: Not Recommended
Date Advice Published: 10 October 2005

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